Team CADASIL is comprised of CADASIL patients, family and friends.  cureCADASIL and the patient community are coming together with Penn Medicine for this rare disease event! CADASIL is a rare, autosomal dominant genetic disorder caused by a mutation of the NOTCH3 gene on the 19th chromosome.  Currently there is no treatment or cure for CADASIL, which strikes adults in the prime of life, progresses relentlessly,  and affects entire families with one diagnosis leading to many more.  The 2019 Million Dollar Bike Ride event is a powerful opportunity to advance research for CADASIL! Each dollar raised up to $30,000 will be doubled through a matching research grant.  Thank you for your support.